What is Ageing?
Ageing is a medical condition classified by WHO. Scientifically, it is the accumulation of a wide variety of molecular and cellular damage over time. The latest advances of medical science have identified nine biological factors that cause cellular ageing, known as the Hallmarks of Ageing. Hundreds of research are being done on each of these biological factors. At Regenosis, we strive to be the first to bring any of this research to a medical possibility when it is ready.
What are the consequences of ageing?
- Gradual deterioration in mental and physical capacity
- High risk of age-related diseases, i.e. heart failures, diabetes, cancers, Alzheimer’s, Parkinson’s disease
- Eventual death
Interventions to promote longevity and cellular repair
Understanding ageing can be beneficial. It can be a modifiable disease risk factor and there are ways to combat a host of debilitating conditions that are now largely untreatable. Taking these factors into consideration, we at Regenosis, have an array of medical solutions and programmes tailored to your needs
- Caloric restriction and intermittent fasting
- Pharmaceutical intervention
- Genetically personalised wellness plan through lifestyle modification
Caloric restriction and intermittent fasting
Caloric restriction (CR) is a dietary regimen that reduces food intake with guidance by professional medical personnel to prevent malnutrition. The three methods of intermittent fasting are alternate-day fasting, periodic fasting, and daily time-restricted feeding. The goal of caloric restriction and intermittent fasting is to induce autophagy, the body’s way of replacing damaged cells with newer, healthier cells.
Never do CR and intermittent fasting without professional guidance as it may lead to:
- Marked fluid and electrolytes shifts
- Complications such as potential life threatening cardiac arrythmia, syncopy & hypotension
- Side effect like fatigue, constipation, cold intolerance
- Long-term side effects including lowering of metabolism, nutrient deficiency/malnutrition, loss of lean muscle mass and lowering the immune system
Medicational therapy can significantly extend lifespan and healthspan. One example is AKG. AKG (alpha-ketoglutarate) is one of the main compounds looked at by world scientists and doctors.
Investigation has been made on the effects of AKG on healthspan and lifespan in mice. Results show that CaAKG (calcium alpha-ketoglutarate) promotes a longer, healthier life by reducing frailty and enhancing longevity. So a person spends more time being well than being unwell. One way to get AKG is RejuvantTM LifeTabsTM, a dietary supplement free from unwanted drug side effects, formulated for men and women to help resist aging.
Lifestyle modification through a genetically personalised plan
This modification deals with knowing what nutrition your body needs, supplemented with good sleeping habits, stress management as well as blood test and genetics to gather insights to modify your lifestyle accordingly.
Nutrition & Exercise
Nutrition is a key component affecting us genetically, biologically and our healthspan. Certain food we eat will cause higher risk of diseases or causes a sugar spike, depending on our genetic makeup, and our present body condition.
Exercise plays an important role in human ageing. It is capable of gene expression change, signalling longevity pathways, and involving epigenetic regulation on the body. Various research and studies have also demonstrated that exercise is beneficial to everyone regardless of age, keeping the brain in better condition through stimulating and maintaining neurogenesis and cognition.
Our body is unique. No matter the condition of body – gender, age, weight, daily activities and lifestyles are variables that make people different. When different people take the same vitamin in the same amount, the results are different. Thus, there is no one-size-fits-all solution.
Many people are taking supplementary vitamins incorrectly all their life. The ones they take, may not be as the important ones they are missing. Take Vitamin D as an example. It’s a very important yet underrated and neglected vitamin found to be insufficient in most people. For them, they will need to have more than the normal amount to solve the insufficiency problem.
Personalised supplements are made by measuring vitamins and minerals according to one’s body composition and current condition to effectively fix health problems directly.
In conclusion, each individual’s genetic make-up and environmental surroundings play an important role in determining their health status. Increasing evidence indicates that environmental and lifestyle factors exert an influence on epigenetic mechanisms, such as DNA methylation, histone modification, and microRNA express, and this may be related to longevity or a greater inclination to diseases.